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XX International Grassland Congress: Offered papers
Cited by. Back to tab navigation Download options Please wait Article type: Other. DOI: Download Citation: J. Biomedical Science from the Ulm University in Germany. Increasing urbanization and air pollution are a few of the warning signs that more investment is needed to keep improving conditions through new technology, research and academic development.
In what departments or degree programs are toxicology classes taught? Some institutes also provide toxicology classes such as the Nutrition Research Institute and the Chulabhorn Research Institute. I have also had my research published in the journal of the Thai Society of Toxicology. Subsequently, I collaborated with Dr. Herman Autrup on health risk assessment research among a population of Thai workers.
My research was published and I received an award for the best oral presentation from the Thai Society of Toxicology.
In I was selected by SOT as a Global Senior Scholar, which encouraged me to develop new perspectives and explore research and academic collaborations with past president of SOT who is an expert in immunotoxicology. These research activities marked by such dynamic exchanges of ideas with senior scientists broadened my view of toxicological research in the field of occupational toxicology.
I still hope to bring and explore new ideas and research strategies to my home country from every congress or meeting I attend to develop academic service and research to create a healthier workplace in Thailand. I came to United States with a grant from the Scientific and Technological Research Council of Turkey in and after one year, I was offered a guest researcher position for four more years.
Here, we are mainly focused on developing robust standardized techniques for DNA damage and repair assessments, which is an emerging and trending topic in the last decade. This increasing awareness of the importance of oxidative DNA damage and its repair to human health makes it exceedingly important to understand, at the fundamental level, the mechanisms of oxidative DNA damage, and its processing by DNA repair enzymes as well as how unrepaired DNA lesions may lead to cytotoxicity, mutagenesis and eventually to diseases and aging.
Last year , our group published eight papers in high-impact journals presenting the importance of our work done in NIST labs. However, in my opinion, Turkey is a little bit exceptional compared with most of the other middle income and developing countries due to the presence of a very powerful national society, The Turkish Society of Toxicology TST.
Our society has almost members and has been very active nationally and all over the world in the last couple of decades by hosting many important international meetings and training courses. Our active society has always been and will always be an important place for young toxicologists in Turkey to establish ties and grow their professional networks. Higher education establishments are found at the university level and toxicology in Turkey is a graduate program, offered mostly in schools of pharmacy and in schools of veterinary medicine.
As clearly seen, the graduate programs in toxicology are quite popular among a wide scope of professions, which is an important indicator of the impact of toxicology in Turkey. Since then, I have participated in almost all the activities of our society, without any hesitation. It may seem impossible, but by my calculation, I have taken part in almost a hundred TST activities sometimes contributing in small ways and other times in very significant ways.
The size of our activities vary from small seminars focused around a well-known scientist to congresses that attract over a thousand participants. Every activity has had a common denominator for me—I have received great returns back from volunteering my time by increasing my presence and reputation among my excellent, devoted TST colleagues. I should also mention that being a member of a strong society taught me the ropes of organizing events with an established level of excellence for the benefit of every member.
Besides contributing to the organization of the scientific events, I also served as the editor of the bi-annual TST bulletin for several years. To learn more about our excellent society, please visit us at www. Like many scientific disciplines, toxicology is a living, breathing science ever dynamic and changing.
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Toxicologists must leave the lab to observe their surroundings and participate in as many learning and teaching opportunities as possible. I would also suggest they participate in the activities of their national society and always keep in mind: The stronger your society, the stronger you are! Besides that, I have met with very important scientists in the field and will soon start collaborating with some of them. Finally, I would like to thank IUTOX for creating travel award opportunities, especially for middle and low income countries, which are home to many intelligent, hardworking, dedicated toxicologists who are often restricted to attend scientific meetings, not by their will or their interest, but by limited travel budgets.
The awardees are either junior or senior scientists from countries where toxicology is underrepresented and they must have either an active research program or currently be active in the practice of toxicology. Congratulations to all of our award winners! Throughout his life, Michael made numerous contributions to toxicology and risk assessment and was an inspiration to his peers. Taking part in the Annual Scientific Meeting and getting to know professionals in the field can open up opportunities for students down the road. The Annual Scientific Meeting ASM on 22—23 September will offer an advanced learning environment by providing an open platform for discussion, debate and professional development in the industry.
Research papers addressing the ASM theme and contemporary issues in toxicology and health risk assessment will also be presented by ACTRA members and industry experts over the course of the two days. Submissions close 31 July Students do not need to be members of ACTRA, however proof of student status will be required upon application.
Submissions close 30 June Both the Annual Scientific Meeting and Continuing Education day will attract an audience of toxicologists, environment health risk assessors, consultants, environmental managers, industrialists, government officials, chemical regulators, policy makers, research scientists, and postgraduate students studying in the field catering to influential personnel in commercial, academic and government sectors. This three-day event will allow delegates to share their research findings and field experience; discuss their insights into important technical issues; build their personal and company profile; network with peers; meet other academics and specialists from other disciplines; advance their knowledge and research; and allow delegates to set the agenda in their sector.
Early Bird Registration closes 12 August, Group discounts and student rates are available. In the past ten years, ACTRA has organized several workshops on regulatory toxicology as stand-alone workshops or in conjunction with themed sessions at the Annual Scientific Meetings.
Since marks the 10th anniversary of the formation of ACTRA, it is timely that ACTRA has developed a workshop to review the current state of regulatory toxicology in Australia to highlight current issues in health risk assessment and to invite discussion of what might assist Australian chemicals and environmental health regulators over the next decade.
The workshop is relevant to government, industry and consultant scientists who deal with the chemical regulatory system in Australia.
Individual Offers
Early bird registration opens in May. All RSN Agencies will receive a discounted rate for groups of five or more members per agency before 30 June The selection of candidates and the award ceremony takes place under the responsibility of a committee chaired by the president of the association. This year, six entries that were all of good quality, were assessed.
The award committee had a hard time to choose the best thesis as the topics where rather diverse and across the diversity of toxicology. The research described in this thesis, shows that glargine has an increased mitogenic potential, but that there is no direct evidence that this also leads to an increased risk of developing cancer in a living organism.
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All other commercial insulin analogues were not found to induce increased cell division as compared to normal human insulin. This is an original combination of state-of-the-art techniques and original hypothesis mechanistic approach. Parts of the thesis were published in journals with good impact. Very original presentation with additional photos to beginning each chapter. Millions of diabetic patients use insulin-like molecules, also called insulin analogues, to regulate their blood glucose levels. Besides the improved pharmacokinetic parameters it was found that some of these analogues have an increased binding affinity for the cancer-related insulin like growth factor 1 receptor IGF1R.
To get a better insight into insulin analogue induced carcinogenicity, we extensively investigated the carcinogenic potential of all clinically available insulin analogues. We demonstrated that one insulin analogue glargine induced tumor cell growth via IGF1R activation in human breast cancer cell line model. However, in the human body the injected glargine is rapidly metabolized into M1 and M2, these glucose lowering metabolites did not show an increased activation of mitogenic pathways or lead to increased cell proliferation.
This model develops spontaneous human relevant mammary gland tumors in about 50 weeks. We found that frequent injections with insulin analogues did not decrease the tumor latency time in this model. Fifty of these tumors were isolated and via next generation sequencing we found that none of the chronic insulin analogue treatments induced genetic instability. Overall, we found no compelling evidence that any of the clinical available insulin analogue increases breast cancer risk.
We think that with this research we have contributed to the improvement of the quality and consistency of the preclinical safety data supporting the development of insulin analogues. Bas ter Braak was born in Zelhem, The Netherlands, in Since then he is employed as a postdoctoral researcher at the Leiden University on a project in which cell signalling reporter stem cell models are established for the mechanistic understanding of liver disease. In the first months of , and by coincidence all in March, our specialty sections have organized a few professional meetings.
The section Teratology and Reproduction Toxicology organized a symposium with presentations on:. The annual meeting was held on the 1st of June in connection with the PhD-days.